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GT16884

CSHL Arabidopsis genetrap mutant lines

Original: GT16884

Phenotypes

Morphological phenotypes

Specific phenotypes were NOT observed.

Original: GT16884

Determination of insertion point(s)

  • 5 prime edge [+] show sequence

    1. Chromosome: 4; Position: 907831 [Map]; Strand: c
      • AT4G02070.2 - [+] show detail - MUTS homolog 6
        Distance: 0; Region: exon5 (CDS)
      • AT4G02070.1 - [+] show detail - MUTS homolog 6
        Distance: 0; Region: exon5 (CDS)
    Flanking Genome Sequence: GT16884 - 5-prime edge 
    ATCCTACTTT CTCCCTGCAT AACAAACAGT TACCTTCATG TACTGTATAT 
    CTAGTTCCTT GGCTCCTACA TGTGCATCCA TCTCAAAAAG CTCATAGAAT 
    TTACCCATCT GCTTGCCACA AAAGAAGAAC ATTTATCCTG GAATCTCCCA 
    TCAATAAATA AGTTATAACT AAATAAGTAG TTATCATTCT ACCTTGAAGA 
    ATACAACTTT GTCCATATGC TTTGATTTAA ACTCCCACCA TTGTCTCTGG 
    AAAAAGGCCA CAAAATCATA TAAGTGAAAG TTGATTAGCT CACCAAAAAA 
    TCCTTAACCA AATTTCCATG TGCTCTTGTT ACCTGGCCTC CTGTTAATTT 
    TTTCACAAAA TCAGGAGGGA GGTAGAGTGT CCTCGGATCA TAATTCTCAT 
    CAGTAGGGCG TCTCCTTTTA GCATCCCTTC GGTCTCTGTT CACCAAAGAT 
    AATTAACAGA ACAAACTTAG CTCAAATAGG GATCATGCAG CCTACTAATA 
    CATCATGAAG TTAAAAGAAA ATC

AT4G02070.1

Model type
Protein coding
Short Description
MUTS homolog 6
Curator Summary
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.
Computational Description
MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1); Has 29702 Blast hits to 21889 proteins in 2967 species: Archae - 234; Bacteria - 11721; Metazoa - 3243; Fungi - 2118; Plants - 3658; Viruses - 802; Other Eukaryotes - 7926 (source: NCBI BLink).
Link
InterPro Scan - TAIR

AT4G02070.2

Model type
Protein coding
Short Description
MUTS homolog 6
Curator Summary
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.
Computational Description
MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1).
Link
InterPro Scan - TAIR