DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain
Curator Summary
Encodes a plant small ubiquitin-like modifier (SUMO) E3 ligase that is a focal controller of Pi starvation-dependent responses. Also required for SA and PAD4-mediated R gene signalling, which in turn confers innate immunity in Arabidopsis. Also involved in the regulation of plant growth, drought responses and freezing tolerance. This latter effect is most likely due to SIZ1 dependent ABI5 sumoylation. Regulates leaf cell division and expansion through salicylic acid accumulation. signaling
Computational Description
SIZ1; CONTAINS InterPro DOMAIN/s: DNA-binding SAP (InterPro:IPR003034), Zinc finger, MIZ-type (InterPro:IPR004181), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G41580.1); Has 1186 Blast hits to 1185 proteins in 207 species: Archae - 0; Bacteria - 6; Metazoa - 654; Fungi - 241; Plants - 117; Viruses - 0; Other Eukaryotes - 168 (source: NCBI BLink).
DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain
Curator Summary
Encodes a plant small ubiquitin-like modifier (SUMO) E3 ligase that is a focal controller of Pi starvation-dependent responses. Also required for SA and PAD4-mediated R gene signalling, which in turn confers innate immunity in Arabidopsis. Also involved in the regulation of plant growth, drought responses and freezing tolerance. This latter effect is most likely due to SIZ1 dependent ABI5 sumoylation. Regulates leaf cell division and expansion through salicylic acid accumulation. signaling
Computational Description
SIZ1; CONTAINS InterPro DOMAIN/s: DNA-binding SAP (InterPro:IPR003034), Zinc finger, MIZ-type (InterPro:IPR004181), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G41580.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain
Curator Summary
Encodes a plant small ubiquitin-like modifier (SUMO) E3 ligase that is a focal controller of Pi starvation-dependent responses. Also required for SA and PAD4-mediated R gene signalling, which in turn confers innate immunity in Arabidopsis. Also involved in the regulation of plant growth, drought responses and freezing tolerance. This latter effect is most likely due to SIZ1 dependent ABI5 sumoylation. Regulates leaf cell division and expansion through salicylic acid accumulation. signaling
Computational Description
SIZ1; CONTAINS InterPro DOMAIN/s: Zinc finger, MIZ-type (InterPro:IPR004181), DNA-binding SAP (InterPro:IPR003034), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G41580.1); Has 1181 Blast hits to 1180 proteins in 204 species: Archae - 0; Bacteria - 0; Metazoa - 655; Fungi - 241; Plants - 117; Viruses - 0; Other Eukaryotes - 168 (source: NCBI BLink).
DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain
Curator Summary
Encodes a plant small ubiquitin-like modifier (SUMO) E3 ligase that is a focal controller of Pi starvation-dependent responses. Also required for SA and PAD4-mediated R gene signalling, which in turn confers innate immunity in Arabidopsis. Also involved in the regulation of plant growth, drought responses and freezing tolerance. This latter effect is most likely due to SIZ1 dependent ABI5 sumoylation. Regulates leaf cell division and expansion through salicylic acid accumulation. signaling
Computational Description
SIZ1; CONTAINS InterPro DOMAIN/s: Zinc finger, MIZ-type (InterPro:IPR004181), DNA-binding SAP (InterPro:IPR003034), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G41580.1); Has 1191 Blast hits to 1190 proteins in 207 species: Archae - 0; Bacteria - 6; Metazoa - 659; Fungi - 241; Plants - 117; Viruses - 0; Other Eukaryotes - 168 (source: NCBI BLink).
DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain
Curator Summary
Encodes a plant small ubiquitin-like modifier (SUMO) E3 ligase that is a focal controller of Pi starvation-dependent responses. Also required for SA and PAD4-mediated R gene signalling, which in turn confers innate immunity in Arabidopsis. Also involved in the regulation of plant growth, drought responses and freezing tolerance. This latter effect is most likely due to SIZ1 dependent ABI5 sumoylation. Regulates leaf cell division and expansion through salicylic acid accumulation. signaling
Computational Description
SIZ1; CONTAINS InterPro DOMAIN/s: DNA-binding SAP (InterPro:IPR003034), Zinc finger, MIZ-type (InterPro:IPR004181), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G41580.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).