cytochrome P450, family 710, subfamily A, polypeptide 1
Curator Summary
Encodes a protein with C22-sterol desaturase activity. The enzyme was shown to catalyze in the presence of NADPH the conversion of β-sitosterol to stigmasterol, but not that of 24-epi-campesterol to brassicasterol (unlike CYP710A2).
Computational Description
cytochrome P450, family 710, subfamily A, polypeptide 1 (CYP710A1); FUNCTIONS IN: C-22 sterol desaturase activity, oxygen binding; INVOLVED IN: oxidation reduction; LOCATED IN: endomembrane system; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: LP.04 four leaves visible, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 710, subfamily A, polypeptide 2 (TAIR:AT2G34490.1); Has 25674 Blast hits to 25623 proteins in 1435 species: Archae - 46; Bacteria - 2777; Metazoa - 10394; Fungi - 4411; Plants - 7239; Viruses - 0; Other Eukaryotes - 807 (source: NCBI BLink).
